(Reuters Health) – Despite plenty of evidence that people with low
levels of “good” cholesterol are more prone to heart attacks, a large
new study suggests that the lacking lipid is not to blame.
The analysis of data on nearly 70,000 people in Denmark affirmed the
link between low levels of high-density lipoprotein (HDL), the
so-called “good” cholesterol, and raised heart attack risk in the
general population. But in people with a gene mutation that lowers
HDL, heart attack risk was not found to be higher at all.
“Association itself doesn’t mean causality,” said lead author Dr. Ruth
Frikke-Schmidt, a consultant in the Department of Clinical
Biochemistry at Rigshospitalet in Copenhagen.
The Journal of Clinical Endocrinology and
Metabolism, online November 16, 2011.