Lunasin – Powerful Amino Acid

So lunasin might be the crazy amino acid but not really 🙂 (really bad joke).

No but in all seriousness lunasin shows promise as a nutrient on the war on cancer.  Will it work alone in a pill ? Probably not but in a whole food it seems to. So which foods contain high amounts of this Amino Acid?
Soy foods and Whole Grains

According to Science Daily:
ScienceDaily (Dec. 2, 2009) — Two new University of Illinois studies report that lunasin, a soy peptide often discarded in the waste streams of soy-processing plants, may have important health benefits that include fighting leukemia and blocking the inflammation that accompanies such chronic health conditions as diabetes, heart disease, and stroke.
http://www.sciencedaily.com/releases/2009/12/091202153946.htm

According to NIH:
An epigenetic mechanism of action is proposed whereby lunasin selectively kills cells being transformed or newly transformed by binding to deacetylated core histones exposed by the transformation event, disrupting the dynamics of histone acetylation-deacetylation and leading to cell death.
http://www.ncbi.nlm.nih.gov/pubmed/15730231

Studies have demonstrated that adequate nutrition with certain types of foods containing bioactive compounds might offer significant protection against carcinogenesis. Soybeans contain a variety of phytochemicals with demonstrated anticancer activity, including isoflavones, protease inhibitors, and more recently lunasin, a novel cancer preventive seed peptide. Initially isolated from soybean, lunasin has also been reported in barley and wheat. The purpose of this review is to summarize the most recent evidence on the possible benefits of lunasin for cancer prevention.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746573/

Synthesis of the Cancer Preventive Peptide Lunasin by Lactic Acid Bacteria During Sourdough Fermentation.
This study shows that fermentation by lactic acid bacteria increased the concentration of lunasin to levels that would suggest new possibilities for the biological synthesis and for the formulation of functional foods.
http://www.ncbi.nlm.nih.gov/pubmed/22098174

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